Dr. Marty Makary has stepped down as the FDA Commissioner after facing weeks of intense pressure and criticism from various stakeholders, including pharmaceutical CEOs and lobbying groups. His resignation follows a tumultuous period marked by disagreements over issues such as flavored vaping products and abortion access. In the wake of his departure, FDA’s top food official, Diamantas, has been appointed as the acting commissioner. This leadership change comes as the Trump administration navigates through agency chaos, raising concerns about its impact on public health and regulatory credibility.