As the NFL season kicks off, fantasy football enthusiasts are strategizing their lineups for Week 1. Experts like Justin Boone offer lineup picks and advice on who to start and sit, emphasizing players like Kyler Murray and David Montgomery as potential standout performers. Meanwhile, some players, including Terry McLaurin and Christian Watson, are highlighted as potential fades this week. The focus on matchups reveals who might thrive or struggle, with insights into the best and worst defenses to target. Additionally, fantasy analysts provide bold predictions and identify sleepers that could exceed expectations, keeping fans engaged and ready for the thrill of the opening games.